Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables identical protein binding activity. Acts upstream of or within several processes, including cytotoxic T cell differentiation; defense response to virus; and positive regulation of calcium-mediated signaling. Located in external side of plasma membrane. Part of receptor complex. Is expressed in several structures, including endocrine gland; exocrine gland; genitourinary system; gut; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human CD8A (CD8 subunit alpha).