Automated description from the Alliance of Genome Resources
Predicted to have lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of cytokine production; and toll-like receptor 4 signaling pathway. Localizes to the external side of plasma membrane and membrane raft. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and perinatal necrotizing enterocolitis. Is expressed in several structures, including femur; gallbladder; intestine; reproductive system; and telencephalon. Orthologous to human CD14 (CD14 molecule).