Automated description from the Alliance of Genome Resources
Exhibits voltage-gated calcium channel activity. Involved in several processes, including extraocular skeletal muscle development; myotube differentiation; and skeletal muscle adaptation. Localizes to the T-tubule and sarcoplasmic reticulum. Used to study hypokalemic periodic paralysis. Human ortholog(s) of this gene implicated in hypokalemic periodic paralysis and malignant hyperthermia. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human CACNA1S (calcium voltage-gated channel subunit alpha1 S).