Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables ankyrin binding activity and voltage-gated calcium channel activity. Involved in positive regulation of adenylate cyclase activity; regulation of atrial cardiac muscle cell membrane repolarization; and regulation of potassium ion transmembrane transporter activity. Acts upstream of or within several processes, including calcium ion transmembrane transport; cardiac conduction; and sensory perception of sound. Located in Z disc and plasma membrane. Is active in cochlear hair cell ribbon synapse and presynaptic active zone membrane. Is expressed in alimentary system; central nervous system; genitourinary system; heart; and nasal cavity. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CACNA1D (calcium voltage-gated channel subunit alpha1 D).