Automated description from the Alliance of Genome Resources
Exhibits chromatin binding activity and methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the PcG protein complex; euchromatin; and heterochromatin. Human ortholog(s) of this gene implicated in 46 XY gonadal dysgenesis. Is expressed in several structures, including brain; early conceptus; genitourinary system; immune system; and retina nuclear layer. Orthologous to human CBX2 (chromobox 2).