Automated description from the Alliance of Genome Resources
Exhibits unfolded protein binding activity. Involved in several processes, including chondrocyte development involved in endochondral bone morphogenesis; collagen biosynthetic process; and collagen fibril organization. Localizes to the endoplasmic reticulum. Used to study osteogenesis imperfecta type 10. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 10 and preterm premature rupture of the membranes. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; lower jaw tooth; and skeleton. Orthologous to human SERPINH1 (serpin family H member 1).