Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits several functions, including alpha-catenin binding activity; enzyme binding activity; and transcription factor binding activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and regulation of cellular macromolecule biosynthetic process. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; nucleus; and synaptic membrane. Predicted to colocalize with neuron projection. Used to study autism spectrum disorder; granulosa cell tumor; ovarian cancer; prostate cancer; and urinary bladder cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); medulloblastoma; and pilomatrixoma. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Orthologous to human CTNNB1 (catenin beta 1).