Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have C5L2 anaphylatoxin chemotactic receptor binding activity; cofactor binding activity; and lipid binding activity. Involved in several processes, including positive regulation of endocytosis; positive regulation of immune response; and visual system development. Localizes to cell surface; extracellular space; and protein-containing complex. Is expressed in several structures, including cerebral cortex; extraembryonic component; genitourinary system; hemolymphoid system; and liver. Used to study complement component 3 deficiency. Human ortholog(s) of this gene implicated in several diseases, including complement deficiency (multiple); macular degeneration (multiple); paroxysmal nocturnal hemoglobinuria; sickle cell anemia; and silicosis. Orthologous to human C3 (complement C3).