Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cytokine activity and protein serine/threonine kinase activator activity. Involved in several processes, including BMP signaling pathway; heart development; and mesenchymal cell proliferation involved in ureteric bud development. Acts upstream of or within several processes, including forebrain development; heart development; and positive regulation of cell differentiation. Located in extracellular space. Is active in extracellular region and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and limb. Human ortholog(s) of this gene implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Orthologous to human BMP2 (bone morphogenetic protein 2).