Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables cytokine binding activity; extracellular matrix binding activity; and glycosaminoglycan binding activity. Acts upstream of or within articular cartilage development and bone development. Located in extracellular matrix and sarcolemma. Is expressed in several structures, including genitourinary system; great vessel of heart; heart and pericardium; hemolymphoid system gland; and jaw. Human ortholog(s) of this gene implicated in Meester-Loeys syndrome and X-linked spondyloepimetaphyseal dysplasia. Orthologous to human BGN (biglycan).