Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables hormone activity and hydroxyapatite binding activity. A structural constituent of bone. Involved in several processes, including negative regulation of bone development; regulation of testosterone biosynthetic process; and type B pancreatic cell proliferation. Acts upstream of or within cellular lipid catabolic process; pancreas development; and positive regulation of insulin secretion. Located in extracellular space. Is active in extracellular region. Is expressed in several structures, including bone; forelimb; jaw; rib; and tongue. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein).