Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits protein phosphatase 2A binding activity and transcription factor binding activity. Involved in several processes, including animal organ development; apoptotic signaling pathway; and negative regulation of programmed cell death. Localizes to several cellular components, including mitochondrial membrane; myelin sheath; and nuclear membrane. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and sensory organ. Used to study oligomeganephronia. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; and prostate cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator).