Automated description from the Alliance of Genome Resources
Predicted to have protein homodimerization activity. Involved in several processes, including antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; cellular response to iron(III) ion; and negative regulation of neuron differentiation. Localizes to the external side of plasma membrane. Used to study hemochromatosis and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; inflammatory bowel disease; and primary immunodeficiency disease. Is expressed in brain; early conceptus; germ cell of ovary; and liver. Orthologous to human B2M (beta-2-microglobulin).