Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables signaling receptor activity. Involved in positive regulation of intracellular signal transduction. Acts upstream of or within response to cytokine. Predicted to be located in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including central nervous system; forelimb bud; heart; metanephros; and sensory organ. Used to study X-linked nephrogenic diabetes insipidus and nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in X-linked nephrogenic diabetes insipidus; nephrogenic diabetes insipidus; and nephrogenic syndrome of inappropriate antidiuresis. Orthologous to human AVPR2 (arginine vasopressin receptor 2).