Automated description from the Alliance of Genome Resources
Exhibits arginase activity. Involved in defense response to protozoan; negative regulation of T-helper 2 cell cytokine production; and negative regulation of activated T cell proliferation. Predicted to localize to several cellular components, including the extracellular space; mitochondrial outer membrane; and neuronal cell body. Used to study hyperargininemia. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human ARG1 (arginase 1).