Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including anion binding activity; cholesterol transfer activity; and lipase binding activity. Involved in several processes, including cholesterol efflux; lipoprotein metabolic process; and triglyceride metabolic process. Localizes to endoplasmic reticulum. Is expressed in several structures, including gut; liver; metencephalon roof; placenta; and yolk sac. Used to study familial hypobetalipoproteinemia 2. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B).