Automated description from the Alliance of Genome Resources
Exhibits several functions, including beta-catenin binding activity; dynein complex binding activity; and enzyme binding activity. Involved in several processes, including animal organ development; cell surface receptor signaling pathway; and regionalization. Localizes to the Scrib-APC-beta-catenin complex; nucleus; and plasma membrane bounded cell projection part. Colocalizes with the cytoplasmic microtubule and microtubule plus-end. Used to study breast cancer; familial adenomatous polyposis; gastrointestinal system cancer (multiple); and reproductive organ cancer (multiple). Human ortholog(s) of this gene implicated in several diseases, including adenoma; carcinoma (multiple); endometrial cancer (multiple); familial adenomatous polyposis 1; and medulloblastoma. Orthologous to human APC (APC regulator of WNT signaling pathway).