Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables tRNA-specific ribonuclease activity. Involved in defense response to other organism; response to yeast; and tRNA destabilization. Located in growth cone and neuronal cell body. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and respiratory system. Human ortholog(s) of this gene implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Orthologous to human ANG (angiogenin).