Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables fructose-1-phosphate aldolase activity and fructose-bisphosphate aldolase activity. Involved in fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and olfactory epithelium. Human ortholog(s) of this gene implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus. Orthologous to human ALDOB (aldolase, fructose-bisphosphate B).