Automated description from the Alliance of Genome Resources (Release 5.3.0)
Predicted to enable identical protein binding activity. Involved in several processes, including positive regulation of cellular component organization; retina morphogenesis in camera-type eye; and tube morphogenesis. Acts upstream of or within several processes, including non-motile cilium assembly; photoreceptor cell outer segment organization; and retina development in camera-type eye. Located in microtubule organizing center and photoreceptor cell cilium. Part of MKS complex. Is expressed in several structures, including brain; ganglia; olfactory epithelium; retina; and trigeminal nerve. Used to study Joubert syndrome 3 and nephronophthisis. Human ortholog(s) of this gene implicated in Joubert syndrome 3; Joubert syndrome 4; and autism spectrum disorder. Orthologous to human AHI1 (Abelson helper integration site 1).