Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable angiotensin receptor activity; bradykinin receptor binding activity; and protein heterodimerization activity. Involved in regulation of blood pressure. Acts upstream of or within several processes, including blood vessel development; drinking behavior; and regulation of systemic arterial blood pressure by circulatory renin-angiotensin. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; artery disease (multiple); chronic kidney disease; neurodegenerative disease (multiple); and sarcoidosis. Orthologous to human AGTR1 (angiotensin II receptor type 1).