Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential and beta1-adrenergic receptor activity. Involved in positive regulation of cold-induced thermogenesis and regulation of circadian sleep/wake cycle, sleep. Acts upstream of or within several processes, including brown fat cell differentiation; diet induced thermogenesis; and regulation of systemic arterial blood pressure by norepinephrine-epinephrine. Located in membrane. Is active in Schaffer collateral - CA1 synapse and neuronal dense core vesicle. Is expressed in several structures, including brain; exocrine gland; hemolymphoid system gland; intestine; and liver and biliary system. Human ortholog(s) of this gene implicated in several diseases, including chronic obstructive pulmonary disease; hypertension (multiple); low tension glaucoma; obstructive sleep apnea; and periodontitis. Orthologous to human ADRB1 (adrenoceptor beta 1).