Automated description from the Alliance of Genome Resources (Release 3.1.1)
A structural constituent of cytoskeleton. Involved in cellular response to interferon-gamma; sarcomere organization; and synaptic vesicle endocytosis. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; basal body patch; and calyx of Held. Is expressed in central nervous system; early conceptus; oocyte; and retina. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20. Orthologous to human ACTG1 (actin gamma 1).