Automated description from the Alliance of Genome Resources (Release 5.2.2)
Contributes to acetylcholine binding activity and acetylcholine-gated cation-selective channel activity. Involved in acetylcholine receptor signaling pathway. Acts upstream of or within regulation of membrane potential. Located in plasma membrane. Part of acetylcholine-gated channel complex. Is active in neuromuscular junction. Is integral component of postsynaptic specialization membrane. Is expressed in diaphragm; skeletal musculature; somite; and trunk. Used to study congenital myasthenic syndrome 3A. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 3A; congenital myasthenic syndrome 3B; and congenital myasthenic syndrome 3C. Orthologous to human CHRND (cholinergic receptor nicotinic delta subunit).