Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in positive regulation of transmission of nerve impulse. Acts upstream of or within several processes, including behavioral response to nicotine; neuronal action potential; and synaptic transmission involved in micturition. Is active in cholinergic synapse. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and thymus. Human ortholog(s) of this gene implicated in cocaine abuse; lung cancer (multiple); and oral cavity cancer. Orthologous to human CHRNB4 (cholinergic receptor nicotinic beta 4 subunit).