Automated description from the Alliance of Genome Resources
Exhibits acetylcholine-gated cation-selective channel activity. Predicted to contribute to acetylcholine binding activity; acetylcholine receptor activity; and extracellular ligand-gated ion channel activity. Involved in several processes, including learning or memory; nervous system development; and regulation of circadian sleep/wake cycle, sleep. Localizes to several cellular components, including the cholinergic synapse; dopaminergic synapse; and integral component of plasma membrane. Used to study attention deficit hyperactivity disorder; autism spectrum disorder; and autosomal dominant nocturnal frontal lobe epilepsy 3. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy and autosomal dominant nocturnal frontal lobe epilepsy 3. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human CHRNB2 (cholinergic receptor nicotinic beta 2 subunit).