Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity; heterocyclic compound binding activity; and quaternary ammonium group binding activity. Predicted to contribute to acetylcholine receptor activity. Predicted to be involved in several processes, including cellular response to nicotine; modulation of inhibitory postsynaptic potential; and synaptic signaling. Predicted to act upstream of or within monoatomic ion transport. Located in cell periphery. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and spinal cord. Human ortholog(s) of this gene implicated in autosomal dominant nocturnal frontal lobe epilepsy 4 and benign familial infantile seizures 6. Orthologous to human CHRNA2 (cholinergic receptor nicotinic alpha 2 subunit).