Automated description from the Alliance of Genome Resources
Exhibits several functions, including ATP binding activity; metal ion binding activity; and signaling receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; hematopoietic or lymphoid organ development; and regulation of signal transduction. Localizes to several cellular components, including the actin cytoskeleton; cell leading edge; and nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; chronic myeloid leukemia; and precursor B lymphoblastic lymphoma/leukemia. Orthologous to human ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase).