Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including ATP binding activity; metal ion binding activity; and signaling receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; hematopoietic or lymphoid organ development; and regulation of signal transduction. Localizes to several cellular components, including actin cytoskeleton; cell leading edge; and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute myeloid leukemia; and chronic myeloid leukemia. Orthologous to human ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase).