Automated description from the Alliance of Genome Resources (Release 5.0.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including negative regulation of muscle cell differentiation; regulation of insulin secretion involved in cellular response to glucose stimulus; and type B pancreatic cell differentiation. Acts upstream of or within blastocyst hatching and negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleolus. Is expressed in early conceptus; nervous system; neural retina; and secondary oocyte. Orthologous to human ZBED6 (zinc finger BED-type containing 6).