Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits complement component C3b binding activity and heparin binding activity. Localizes to extracellular space. Human ortholog(s) of this gene implicated in several diseases, including COVID-19; atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; and lupus nephritis. Orthologous to human CFH (complement factor H).