Automated description from the Alliance of Genome Resources (Release 5.1.1)
Enables complement component C3b binding activity and heparin binding activity. Predicted to be involved in regulation of complement activation. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; eye disease (multiple); hemolytic-uremic syndrome; lupus nephritis; and systemic lupus erythematosus. Orthologous to human CFH (complement factor H).