Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits ionotropic glutamate receptor binding activity and synaptic receptor adaptor activity. Involved in several processes, including dendritic spine morphogenesis; learning or memory; and regulation of signal transduction. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density. Colocalizes with ionotropic glutamate receptor complex and postsynaptic membrane. Is expressed in cerebral cortex. Orthologous to human SHANK1 (SH3 and multiple ankyrin repeat domains 1).