Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Kcnk9. (This text reflects annotations as of Wednesday, January 23, 2013.)

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Summary from NCBI RefSeq

[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains, and is highly expressed in the cerebellum. Amplification and overexpression of this gene has been observed in several types of human carcinomas, notably in breast cancer. This gene is imprinted in fetal brain, with preferential expression from the maternal allele. [provided by RefSeq, Oct 2010]

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Summary text based on GO annotations supported by experimental evidence in other organisms

• From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Kcnk9:
  • participates in the following biological processes:
    • potassium ion transport
  • performs the following molecular functions:
    • potassium channel activity
    • protein heterodimerization activity
    • protein homodimerization activity
  • is located in the following cellular components:
    • plasma membrane
    • synaptic vesicle

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Summary text based on GO annotations supported by structural data

• Kcnk9 encodes a protein or proteins that contain the following InterPro domains: Ion transport 2, Two pore domain potassium channel, Two pore domain potassium channel, TASK family, Two pore domain potassium channel, TASK-3, Two pore domain potassium channel, TASK/TWIK, indicating that the gene product:
  • participates in the following biological processes:
    • potassium ion transmembrane transport
  • is located in the following cellular components:
    • integral to membrane
    • membrane

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Kcnk9 indicates that it:
  • participates in the following biological processes:
    • ion transport
    • potassium ion transmembrane transport
    • regulation of ion transmembrane transport
    • transport
  • performs the following molecular functions:
    • ion channel activity
    • voltage-gated ion channel activity
  • is located in the following cellular components:
    • integral to membrane
    • membrane

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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