Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable CCR2 chemokine receptor binding activity. Predicted to be a structural constituent of nuclear pore. Acts upstream of or within lamellipodium assembly and macrophage chemotaxis. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in several structures, including blastocyst; cerebral cortex ventricular layer; early embryo; and extraembryonic component. Human ortholog(s) of this gene implicated in nephrotic syndrome type 17. Orthologous to human NUP85 (nucleoporin 85).