Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables inorganic diphosphate transmembrane transporter activity. Involved in several processes, including cementum mineralization; diphosphate metabolic process; and inhibition of non-skeletal tissue mineralization. Located in plasma membrane. Is active in extracellular region. Is expressed in several structures, including bone; connective tissue; olfactory epithelium; telencephalon; and vibrissa follicle. Used to study craniometaphyseal dysplasia. Human ortholog(s) of this gene implicated in autosomal dominant craniometaphyseal dysplasia and chondrocalcinosis. Orthologous to human ANKH (ANKH inorganic pyrophosphate transport regulator).