Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have Rac guanyl-nucleotide exchange factor activity and phospholipid binding activity. Involved in several processes, including neutrophil chemotaxis; positive regulation of GTPase activity; and positive regulation of substrate adhesion-dependent cell spreading. Predicted to localize to several cellular components, including dendritic shaft; growth cone; and perinuclear region of cytoplasm. Used to study autism spectrum disorder. Is expressed in several structures, including liver; nervous system; palatal shelf; skeleton; and testis. Orthologous to human PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1).