Automated description from the Alliance of Genome Resources
Predicted to have NAD(P)H oxidase activity; calcium ion binding activity; and superoxide-generating NADPH oxidase activity. Involved in several processes, including animal organ development; growth; and thyroid hormone metabolic process. Predicted to localize to several cellular components, including the NADPH oxidase complex; cell leading edge; and cell surface. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital hypothyroidism. Is expressed in placenta and thyroid gland. Orthologous to human DUOX2 (dual oxidase 2).