Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis and stem cell differentiation. Predicted to be located in nucleoplasm. Is expressed in several structures, including branchial arch; extraembryonic component; genitourinary system; immune system; and intestine. Orthologous to human ZNF281 (zinc finger protein 281).