Automated description from the Alliance of Genome Resources (Release 7.0.0)
Involved in radial spoke assembly. Acts upstream of or within epithelial cilium movement involved in extracellular fluid movement; establishment of localization in cell; and maintenance of ciliary planar beating movement pattern. Located in 9+2 motile cilium and axoneme. Part of radial spoke head 1; radial spoke head 2; and radial spoke head 3. Is expressed in lateral ventricle choroid plexus; lung epithelium; metencephalon part of 4th ventricle choroid plexus; and nasal cavity respiratory epithelium. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 11. Orthologous to human RSPH4A (radial spoke head component 4A).