Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in ameloblast differentiation; amelogenesis; and regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex and chromatin. Is expressed in several structures, including central nervous system; genitourinary system; oral region epithelium; and tooth. Orthologous to human ASCL5 (achaete-scute family bHLH transcription factor 5).