Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits identical protein binding activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; nervous system development; and paranodal junction maintenance. Localizes to several cellular components, including USH2 complex; cytoskeleton; and periciliary membrane compartment. Predicted to colocalize with neuronal cell body. Is expressed in several structures, including central nervous system; cervical intervertebral disc; forelimb bud; sensory organ; and thymus. Used to study Usher syndrome type 2D and autosomal recessive nonsyndromic deafness 31. Human ortholog(s) of this gene implicated in Usher syndrome type 2D; autosomal recessive nonsyndromic deafness 31; and sensorineural hearing loss. Orthologous to human WHRN (whirlin).