Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have aspartic-type endopeptidase inhibitor activity. Involved in several processes, including embryonic morphogenesis; maintenance of epithelial cell apical/basal polarity; and positive regulation of BMP signaling pathway. Localizes to apical plasma membrane. Is expressed in early conceptus and embryo. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 9 and ventriculomegaly - cystic kidney disease. Orthologous to human CRB2 (crumbs cell polarity complex component 2).