Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 4.0)

Predicted to enable ATPase-coupled transmembrane transporter activity; apolipoprotein A-I receptor binding activity; and lipid transporter activity. Involved in several processes, including corneocyte desquamation; positive regulation of intracellular lipid transport; and regulation of insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within several processes, including positive regulation of cholesterol efflux; positive regulation of protein localization to cell surface; and skin development. Located in cytosol. Is expressed in adrenal gland; epidermis; and gland. Used to study autosomal recessive congenital ichthyosis 4B. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1; autosomal recessive congenital ichthyosis 4A; and autosomal recessive congenital ichthyosis 4B. Orthologous to human ABCA12 (ATP binding cassette subfamily A member 12).

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Gene Ontology Evidence Code Abbreviations:

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