Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable CCR6 chemokine receptor binding activity and identical protein binding activity. Predicted to be involved in cAMP-mediated signaling; defense response to other organism; and positive regulation of flagellated sperm motility involved in capacitation. Predicted to act upstream of or within defense response to bacterium. Predicted to be located in membrane; microvesicle; and sperm midpiece. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Orthologous to human DEFB1 (defensin beta 1).