Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits extracellularly ATP-gated cation channel activity. Involved in several processes, including response to ATP; skeletal muscle fiber development; and smooth muscle contraction. Localizes to intracellular and plasma membrane. Is expressed in facial ganglion; heart; medulla oblongata basal plate mantle layer; and vagus ganglion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 41. Orthologous to human P2RX2 (purinergic receptor P2X 2).