Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables tryptophan 5-monooxygenase activity. Predicted to be involved in aromatic amino acid metabolic process. Predicted to act upstream of or within serotonin biosynthetic process from tryptophan. Located in neuron projection. Is expressed in several structures, including aorta-gonad-mesonephros; germ cell of ovary; nervous system; retina; and tongue. Used to study melancholic depression. Human ortholog(s) of this gene implicated in autistic disorder; major depressive disorder; and panic disorder. Orthologous to human TPH2 (tryptophan hydroxylase 2).