Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including energy homeostasis; regulation of DNA-templated transcription; and regulation of skeletal muscle cell differentiation. Acts upstream of or within regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study atrioventricular septal defect. Orthologous to human NR1D2 (nuclear receptor subfamily 1 group D member 2).