Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and histone methyltransferase activity. Involved in GABAergic neuron differentiation and hypothalamus cell differentiation. Acts upstream of or within negative regulation of transcription by RNA polymerase II and neurogenesis. Located in nucleus. Is expressed in embryo; future spinal cord; head; and neural tube ventricular layer. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human PRDM13 (PR/SET domain 13).