Automated description from the Alliance of Genome Resources
Exhibits ubiquitin protein ligase activity. Involved in negative regulation of smoothened signaling pathway and protein polyubiquitination. Predicted to localize to the early endosome; nucleus; and plasma membrane. Is expressed in several structures, including genitourinary system; heart; node; and skin. Orthologous to human MGRN1 (mahogunin ring finger 1).