Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable calcium ion binding activity. Involved in several processes, including BMP signaling pathway; embryonic organ development; and fasciculation of sensory neuron axon. Acts upstream of or within coronary vasculature development; determination of digestive tract left/right asymmetry; and determination of heart left/right asymmetry. Located in nucleus. Is expressed in several structures, including branchial arch; ganglia; heart; limb bud; and telencephalon. Used to study Carpenter syndrome and visceral heterotaxy. Human ortholog(s) of this gene implicated in Carpenter syndrome. Orthologous to human MEGF8 (multiple EGF like domains 8).