Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to enable identical protein binding activity. Involved in cell differentiation. Acts upstream of or within several processes, including cellular response to interferon-gamma; epithelial cell development; and skeletal muscle tissue development. Located in several cellular components, including brush border; focal adhesion; and stress fiber. Is expressed in several structures, including alimentary system; brain; limb; sensory organ; and skeleton. Used to study spondylocarpotarsal synostosis syndrome. Human ortholog(s) of this gene implicated in Larsen syndrome; bone development disease (multiple); cleft palate; and spinal disease (multiple). Orthologous to human FLNB (filamin B).